Abstract
Objective: The aim of this study was to explore the feasibility and efficacy of functional preservation surgery combined with radiotherapy in the treatment of malignant tumors of maxillary sinus.
Materials and Methods: The authors retrospectively reviewed 6 cases of malignant tumors of maxillary sinus who had undergone functional preservation resection and were given radical radiotherapy 4 weeks after operation between January 2012 and May 2021. One case underwent radical maxillary sinus surgery, 4 cases lateral rhinotomy, and 1 case partial maxillectomy.
Results: The series included 6 male patients between 42 and 84 years old (average 58.7 years). Pathological types include squamous cell carcinomas (n=2; 1 case of well-differentiated squamous cell carcinomas), adenoid cystic carcinoma (n=2), small round cell malignant tumor with intrastriatal infiltration (n=1), and malignant transformation of inverted papilloma (n=1). Patients were clinically followed up for a median of 72 months (range 37-111 months), and all the 6 cases are alive with good quality of life.
Conclusions: In this single-center report from relatively small series of maxillary sinus malignant tumors, we demonstrate that functional preservative resection combined with radical radiotherapy is generally safe and effective for different types of maxillary sinus malignant lesions.
Keywords:Malignant tumor; radiotherapy; maxillary sinus; lateral rhinotomy; partial maxillectomy
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